Search on: JAGGED1 PROTEIN 
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Descriptor English:   Jagged-1 Protein 
Descriptor Spanish:   Proteína Jagged-1 
Descriptor Portuguese:   Proteína Jagged-1 
Synonyms English:   Alagille Syndrome Protein
Antigen, CD339
CD339 Antigen
Jagged 1
Jagged 1 Protein
Jagged-1
Jagged1 Protein
Serrate 1 Protein
Serrate-1 Protein
Serrate1 Protein  
Tree Number:   D12.644.276.930.500
D12.776.157.125.797.500
D12.776.543.800.500
D23.529.930.500
Definition English:   A serrate-jagged protein that functions as a ligand for NOTCH RECEPTORS. It may regulate CELL DIFFERENTIATION in HEMATOPOIESIS and PHYSIOLOGIC ANGIOGENESIS. Mutations in the Jagged-1 gene are associated with ALAGILLE SYNDROME 1. 
History Note English:   2017 (1991) 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification DF deficiency
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   56530 
Unique Identifier:   D000072100 

Occurrence in VHL:
 

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